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Lauryn Hill

Singer, Songwriter & Record Producer

I had gone through a lot, a huge emotional and spiritual battle prior to the creation of that album. And the funny thing is that while I was going in the battle, I couldn't see my hand to spite my face. I mean, I really couldn't see anything, because I was so emotionally entangled in everything that I've gone through. But it was like, once I was delivered from that situation, and once I got the perspective -- was able to look back at heartache, and look back at pain and disappointment -- for some reason it all was so clear. It was just like the picture started to form itself. The songs started to create themselves. I was able to look back and be a narrator of my own situation. But the interesting thing was that it couldn't happen while I was in the middle of the confusion.
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Sir Edmund Hillary

Conqueror of Mt. Everest

When I was very young I read about it, dreamed about it and when the opportunity came to do something about it I seemed to slip into it rather easily. Even the companionship that I made with similar friends in adventurous activities, I found very, very rewarding. Nothing is better fun that sitting down with a group of your peers who've done similar sort of things and just talking about your experiences. Maybe boasting a little bit here and there too, but sharing experiences that you all appreciate, you all know have been frightening and dangerous and have been successful.
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Sir Edmund Hillary

Conqueror of Mt. Everest

Sir Edmund Hillary: I did have -- definitely -- one heroic figure who impressed me very much indeed, and that was the great Antarctic explorer, Shackleton. Shackleton I always admired because he was a tough man and a very good leader. And whenever he was in difficult circumstances, which he frequently was, he seemed to have the great ability to inspire his men and lead his party safely out of those conditions. So certainly Shackleton, I would have said, more than anything, was a role model for me. And later on, when I was down in the Antarctic myself and doing various adventures, I really felt that I tried to behave perhaps a little bit more like Shackleton, than any of the other famous Antarctic explorers.
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David Ho

AIDS Research Pioneer

There had been an old dogma in the field that HIV comes in and after this acute phase that looks like flu, there's a prolonged dormancy. The virus wasn't doing much and the person is pretty well. And, we know that because we now know that period could be about ten years. And, somehow we realized that during this period the person's immune system is gradually dwindling and I didn't necessarily like the notion that -- we knew the patient is well -- but I didn't necessarily like the notion that the virus is dormant. And, for a long period of time my research effort is to measure the virus, to quantify the virus. I would say that's a decade long effort, having been one of the first to measure how much virus there is, and then very gradually demonstrating that the old notion is incorrect.
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David Ho

AIDS Research Pioneer

The protease structure had been studied for a long time. Particularly in the late '80s we realized what it looked like three dimensionally, and there's a cavity in the middle. And inside that cavity are the enzymatic sites, or the cutting sites. And so, the big proteins could come and sit in this groove and then be cut. Well it was easy to think that if you could fill that cavity with a small chemical so the proteins could not be cut. And so many, many groups started to try to fill that cavity with small chemicals, and there were rationally designed chemicals -- as well as chemicals that were done by a more empirical screening process -- that would fill this cavity. And so, what protease inhibitors are is simply something that would gum up the chemicals. So now HIV could not cut its proteins, and so it makes that progeny, and therefore it can't spread the infection. As long as the patient is taking the drug, it can't spread the infection. So it's now kept in control.
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